Central and peripheral factors contributing to obstructive sleep apneas
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چکیده
منابع مشابه
Central and peripheral factors contributing to obstructive sleep apneas
Apnea, the cessation of breathing, is a common physiological and pathophysiological phenomenon. Among the different forms of apnea, obstructive sleep apnea (OSA) is clinically the most prominent manifestation. OSA is characterized by repetitive airway occlusions that are typically associated with peripheral airway obstructions. However, it would be an oversimplification to conclude that OSA is ...
متن کاملArterial Stiffness Increases During Obstructive Sleep Apneas SLEEP AND BREATHING
OBSTRUCTIVE SLEEP APNEA (OSA) APPEARS TO BE AN INDEPENDENT RISK FACTOR FOR DIURNAL SYSTEMIC HYPERTENSION,1-3 although the biologic markers for this association have not been well worked out. Acute systemic blood pressure (BP) perturbations have been well described in association with obstructive events in patients with OSA,4-8 but arterial vasomotor activity, which may influence BP activity in ...
متن کاملPeripheral vascular resistance increases after termination of obstructive apneas.
The mechanisms by which obstructive apneas produce intermittent surges in arterial pressure remain poorly defined. To determine whether termination of obstructive apneas produce peripheral vasoconstriction, we assessed forearm blood flow during and after obstructive events in sleeping patients experiencing spontaneous upper airway obstructions. In all subjects, heart rate was monitored with an ...
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Obstructive sleep apnea (OSA) is common in patients with refractory epilepsy and may exacerbate seizures. In epileptic patients with OSA, seizures occur more frequently during sleep. Seizure frequency may be reduced by treating OSA and increase if the treatment is interrupted or neglected. It is not clear how OSA provokes seizures. Multiple seizureprovoking factors including cerebral hypoxemia,...
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Considerable progress has been made over the last several decades in our understanding of the pathophysiology of both central and obstructive sleep apnea. Central sleep apnea, in its various forms, is generally the product of an unstable ventilatory control system (high loop gain) with increased controller gain (high hypercapnic responsiveness) generally being the cause. High plant gain can con...
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ژورنال
عنوان ژورنال: Respiratory Physiology & Neurobiology
سال: 2013
ISSN: 1569-9048
DOI: 10.1016/j.resp.2013.06.004